Searchable abstracts of presentations at key conferences in endocrinology

ea0029p748 | Endocrine Disruptors | ICEECE2012

Effects of Quercetin on mRNA expression of Steroidogenesis genes in Primary Cultures of Interstitial Leydig cells treated with Atrazine

Abarikwu S. , Pant A. , Farombi E.

The mechanisms of reproductive malfunction of male mammals caused by atrazine (ATZ) remain unknown. To explore the effects of ATZ on the expressions of StAR (steroidogenic acute regulatory protein), CYP (cytochrome-P450) 11A1, CYP17A1, 3β-HSD (3β-hydroxysteroid dehydrogenase), INSL-3 (insulin-like factor 3), AR (androgen receptor), ER (estrogen receptor), LHR (luteinising hormone receptor) and INH-α (inhibin-alpha), we isolated Leydig cells from healthy immature...